Nanofiber scaffold gradients for interfacial tissue engineering

PLGA nanofiber-coated silk microfibrous scaffold for connective tissue engineering.

A modified degumming technique, involving boiling in 0.25% Na2CO3 with addition of 1% sodium dodecyl sulphate and intermittent ultrasonic agitation, was developed for knitted silk scaffolds. Sericin was efficiently removed, while mechanical and structural properties of native silk fibroin were preserved. Biocompatible and mechanically robust hybrid nano-microscaffolds were fabricated by coating...

fabricating electrospun poly(3-hydroxybutyrate)/hydroxyapatite nanocomposite scaffold for tissue engineering application

. در رســاله ی حاضر، ابتدا داربست نانوالیاف سه بعدی متخلخل به روش الگوبرداری تصویری شبیه سازی شد. با استفاده از طراحی آزمایش به روش تاگوچی پس از ساخت داربست های پلی (3- هیدروکسی بوتیرات) (p3hb) شناسایی رفتار پارامترهای موادی مثل لزجت سیال پلیمر، فراریت و رسانایی الکتریکی محلول پلیمری و پارامترهای دستگاهی مثل دبی حجمی سیال، ولتاژ الکتریکی و فاصله نازل تا جمع کننده صورت گرفت. بعد از محاسبه ی خصوص...

preparation of plga nanofiber scaffold in tissue engineering using electrospinning technique

The Role of Biodegradable Engineered Nanofiber Scaffolds Seeded with Hair Follicle Stem Cells for Tissue Engineering

Background: The aim of this study was to fabricate the poly caprolactone (PCL) aligned nanofiber scaffold and to evaluate the survival, adhesion, proliferation, and differentiation of rat hair follicle stem cells (HFSC) in the graft material using electrospun PCL nanofiber scaffold for tissue engineering applications. Methods: The bulge region of rat whisker was isolated and cultured in DMEM: n...

Poly(Limonene Thioether) Scaffold for Tissue Engineering.

A photocurable thiol-ene network polymer, poly(limonene thioether) (PLT32o), is synthesized, characterized, fabricated into tissue engineering scaffolds, and demonstrated in vitro and in vivo. Micromolded PLT32o grids exhibit compliant, elastomeric mechanical behavior similar to grids made of poly(glycerol sebacate) (PGS), an established biomaterial. Multilayered PL32o scaffolds with regular, g...